Raman Flow Cell

Brand: Endress+Hauser

Raman Flow Cell

Brand: Endress+Hauser

Local Support: Authorized Distributor Serving Alabama, Mississippi, Louisiana, Florida, New York, Connecticut, Massachusetts, Vermont, New Hampshire, Maine, Rhode Island, Puerto Rico, US Virgin Islands and parts of Tennessee and Arkansas.

Extended Extended

The Raman flow cell meets the speed demands of downstream by optimizing Raman collection for low-turbidity, low volume samples. Ideally suited for development-scale flow rates, the Raman flow cell allows real-time monitoring, rapid process optimization, and process control for chromatography and other downstream unit operations.

  • Downstream: aggregation, protein crystallization, formula stability, product CQA, protein concentration, buffer excipients
Features
  • TheRaman flow benchhouses a Raman flow cell and easily connects to anRxn-10 probepaired with a Raman Rxn embedded analyzer, and ensures transferability when used with theRaman flow assembly calibration and verification kit
  • Provides continuous, real-time measurements with high sensitivity for development-scale flow rates
  • Achieves lower limits of detection through enhancement of the Raman signal
  • Brings Raman-based process insights and control to downstream bioprocessing unit operations

Specifications

Product Family

  • Raman

Measuring Principle

  • Raman Spectroscopy

Temperature

  • Operating: 0 to 40 °C (32 to 104 °F)
  • Storage: -20 to 60 °C (-4 to 140 °F)

Relative Humidity

  • Storage: < 90 % Non-Condensing

Unit Dimensions (W x H x D)

  • 46 x 25 x 11 mm
  • 1.8 x 1.0 x 0.4 inch

Sampling Probe Compatibility

  • Raman Rxn-10

Sampling Optic Compatibility

  • micro flow bench

Pressure

  • Max pressure: 4.8 barg (70 psig)

Wetted Materials

  • Body: 316L stainless steel
  • Window: Proprietary material, optimized for bioprocesses
  • Surface finish: Ra 15 with Electropolish to ASME BPE SF4 finish
  • Adhesive: USP Class VI and ISO 10993 compatible

Sterilization Method

  • CIP/SIP

Process Connection

  • 5/16-24 flat bottom ferrules
  • Up to 3/16 inch OD tubing

Fluid Path Thickness

  • 2.5 mm

Flow Conditions

  • Laminar

Flow Cell Maximum Volumetric Flowrate

  • 15 mL/min
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