Raman Rxn-45 Probe

Brand: Endress+Hauser

Raman Rxn-45 Probe

Brand: Endress+Hauser
Extended Extended

The Raman Rxn-45 probe capitalizes on the power of Raman in bioprocess manufacturing by measuring multiple, specific components in real-time for continuous, around-the-clock process feedback. It also meets the daunting sampling requirements of compliance, sterilization, port compatibility, and convenience. The Raman Rxn-45 probe was designed for installation in development and cGMP stainless-steel reactors and is successfully used to provide an analytical “eye” into large-scale bioprocesses.

  • Cell culture: glucose, lactate, amino acids, cell density, titer, and more
  • Fermentation: glucose, glycerol, acetate, methanol, ethanol, biomass, and more
Features
  • Measures multiple components in real-time for automated 24/7 process feedback
  • Provides long-term measurement stability
  • Offers a suitable surface finish for cGMP manufacturing
  • Provides compatibility with industry standard bioreactor side ports and sensor housings
  • Offers the flexibility of being installed in development and production reactors
  • Reduces sterilization and cleaning burdens with CIP/SIP standard compatibility

Specifications

Measuring Principle

  • Raman spectroscopy

Laser Wavelength

  • 785 nm, 1000 nm

Spectral Coverage

  • Probe spectral coverage is limited by the coverage of the analyzer being used

Maximum Laser Power Into Probehead (mW)

  • < 499

Sample Interface

  • Temperature ramp: ≤ 30 °C/min; ≤ 54 °F/min
  • Temperature; -30 to 150 °C (-22 to 302 °F)

Pressure

  • Ma xpressure: 13.8 barg (200 psig)

Wetted Materials

  • Body: 316L stainless steel
  • Window: Proprietary material, optimized for bioprocesses
  • Process connection: PG13.5 for industry standard sensor housings, welded port connectors available
  • Surface finish: Ra 15 with electropolish
  • Adhesive: USP Class VI and ISO993 compatible

Fiber Optic Cable

  • Cable sold separately

Length

  • 120 mm / 4.73 inch

Diameter

  • 12 mm / 0.48 inch

Sterilization Method

  • CIP/SIP
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